Bioscience & Medical

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The Bioscience & Medical technology area contains solutions ranging from the medical device, diagnostic, and therapeutic fields to next generation drop-in biofuels, biodefense sensors and detectors, and computational biochemical imaging and software.  

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Miniaturized Chemical Detectors for Point-of-Care Diagnosis
Miniaturized Chemical Detectors for Point-of-Care Diagnosis

Sandia’s mini-PDID makes it possible to diagnose illnesses by identifying...

One-Pot Bioconversion of Distiller's Grains to Advanced Biofuels
One-Pot Bioconversion of Distiller's Grains to Advanced Biofuels

Increases in bioethanol production throughout the US has led to...

RetSynth Software
RetSynth Software

RetSynth is a comprehensive tool for rapidly identifying all optimal...

Quenching of Unincorporated Amplification Signal Reporters (QUASR)
Quenching of Unincorporated Amplification Signal Reporters (QUASR)

Sandia’s QUASR modification to LAMP helps satisfy the requirements for...

Patent Title Patent Number Grant Date
Real-time patch-clamp sensing of transport across a barrier tissue US12540938B1 02/03/2026
New!
Multiplanar planar electromagnetic array US12523654B1 01/13/2026
Lung-targeting single-domain antibodies and purification methods US12421306B1 09/23/2025
Reusable filtering face mask US12364883B2 07/22/2025
Modified yeast microorganisms to increase yield of 3-hydropropionic acid US12215373B1 02/04/2025
Enrichment of amino acids from biomass residuum US12203116B2 01/21/2025
Respirator test system US12161894B1 12/10/2024
Brain-targeting single domain antibodies and purification methods US12098200B1 09/24/2024
Multivalent anti-SARS-CoV-2 nanobodies US12098186B1 09/24/2024
SARS-CoV-2 variant nanobodies and constructs comprising such nanobodies US12091446B1 09/17/2024
Acoustic wave resonator with active shunt capacitance cancellation and systems thereof US12084708B1 09/10/2024
Alkyl dialkoxyalkanoates as bioderived, high cetane diesel fuels US12077719B2 09/03/2024
Apparatus and methods for sample analysis with multi-gradient microfluidics US12070751B1 08/27/2024
Coronavirus neutralizing humanized antibodies and uses thereof US12024551B1 07/02/2024
Devices for studying plant-fungus interactions and for imaging plant roots US11993764B2 05/28/2024
Real-time patch-clamp sensing of transport across a barrier tissue US11885793B1 01/30/2024
Vector measurements using a pulsed, optically pumped atomic magnetometer US11841404B1 12/12/2023
Optically pumped, radio-frequency atomic magnetometry with feedback stabilization US11821966B1 11/21/2023
Methods and systems for opioid detection US11733217B1 08/22/2023
Multifunctional RF limiting amplifier US11722106B1 08/08/2023
CRISPR-Cas based system for targeting single-stranded sequences US11661599B1 05/30/2023
Small molecule inhibitors for treatment of alpha viruses US11564919B1 01/31/2023
Methods of producing lipid-derived compounds and host cells thereof US11560576B1 01/24/2023
Microfluidic package and method of making the same US11554369B2 01/17/2023
Optically pumped gradient magnetometer US11543474B1 01/03/2023
Engineering RuBisCo for food safety US11518989B1 12/06/2022
Alkyl dialkoxyalkanoates as bioderived, high cetane diesel fuels US11492565B1 11/08/2022
Endpoint detection of amplified nucleic acids US11473141B2 10/18/2022
Engineered hosts with exogenous ligninase and uses thereof US11453895B1 09/27/2022
Lipid composition for the delivery of therapeutic cargos US11433121B1 09/06/2022
Solid-state tuning behavior in acoustic resonators US11405014B1 08/02/2022
Real time autonomous surveillance of pathogens US11366116B1 06/21/2022
Enrichment of amino acids from biomass residuum US11326193B1 05/10/2022
Biochemical upgrading of high-protein biomass and grain products US11312978B2 04/26/2022
Compounds that induce octane overboosting US11225622B1 01/18/2022
Functionalized coating polymers and uses thereof US11203702B1 12/21/2021
Fatty acid derived alkyl ether fuels for compression ignition US11193075B1 12/07/2021
Check valves for microfluidic systems and methods thereof US11130129B2 09/28/2021
Promoters and uses thereof US11098306B1 08/24/2021
Therapeutic phages and methods thereof US11066691B1 07/20/2021
Lipid-coated particles for treating viral infections US11045554B1 06/29/2021
Tunable metal-organic framework compositions and methods thereof US11007516B1 05/18/2021
Neural interface methods and apparatus to provide artificial sensory capabilities to a subject US10993665B1 05/04/2021
Modular assemblies and systems for cell cultures and methods thereof US10988723B1 04/27/2021
Protein and nucleic acid detection for microfluidic devices US10981174B1 04/20/2021
Terpene synthases for biofuel production and methods thereof US10947563B2 03/16/2021
Shape-preserving polymeric replication of biological matter US10947349B2 03/16/2021
Octane hyperboosting in fuel blends US10899988B1 01/26/2021
Conversion of lignin into a water-soluble polyacid using a MOF catalyst US10800891B1 10/13/2020
Detection of active and latent infections with microfluidic devices and systems thereof US10786811B1 09/29/2020
Apparatus, method and system for imaging and utilization of SEM charged particles US10770262B1 09/08/2020
Microfluidic platform for multiplexed detection in single cells and methods thereof US10731205B2 08/04/2020
Endpoint detection of amplified nucleic acids US10724091B1 07/28/2020
Microfluidic package and method of making the same US10717079B2 07/21/2020
Miniaturized pulsed discharge ionization detector, non-radioactive ionization sources, and methods thereof US10697934B2 06/30/2020
Biochemical upgrading of high-protein biomass and grain products US10683519B1 06/16/2020
Fluid delivery manifolds and microfluidic systems US10627366B2 04/21/2020
Methods for treating diseases related to the wnt pathway US10624949B1 04/21/2020
Method and apparatus for purifying nucleic acids and performing polymerase chain reaction assays using an immiscible fluid US10590477B2 03/17/2020
Shape-preserving polymeric replication of biological matter US10538632B1 01/21/2020
Check valves for microfluidic systems and methods thereof US10478818B1 11/19/2019
Non-contact temperature control system for microfluidic devices US10406528B1 09/10/2019
Terpene synthases for biofuel production and methods thereof US10400254B1 09/03/2019
Nonaqueous redox flow battery electrolyte comprising an ionic liquid with a metal cation coordinated to redox-active ligands US10305133B2 05/28/2019
Linear peptides that mimic structural epitopes for antibody assays US10267788B1 04/23/2019
Shear horizontal surface acoustic wave (SH-SAW) resonators and arrays thereof US10261078B2 04/16/2019
Miniaturized pulsed discharge ionization detector, non-radioactive ionization sources, and methods thereof US10197532B1 02/05/2019
Trajectory-based triggering system for hyperspectral imaging flow cytometer US10180398B2 01/15/2019
Microsampler and method of making the same US10161835B1 12/25/2018
Sealed micro gas chromatography columns and methods thereof US10151732B1 12/11/2018
Tandem biochemical and thermochemical conversion of algal biomass US10077454B1 09/18/2018
Detection of bioagents using a shear horizontal surface acoustic wave biosensor US10031135B2 07/24/2018
Atomic magnetometer with multiple spatial channels US9995800B1 06/12/2018
High-temperature, adhesive-based microvalves and uses thereof US9995411B1 06/12/2018
Methods of expanding bacteriophage host-range and bacteriophage produced by the methods US9988608B1 06/05/2018
Microfluidic platform for multiplexed detection in single cells and methods thereof US9957554B1 05/01/2018
Optoelectronic system and apparatus for connection to biological systems US9907496B1 03/06/2018
Method and apparatus for purifying nucleic acids and performing polymerase chain reaction assays using an immiscible fluid US9803238B1 10/31/2017
System and method for detecting components of a mixture including a valving scheme for competition assays US9766230B1 09/19/2017
Massively parallel diffuse optical tomography US9750413B2 09/05/2017
Metal-organic framework catalysts for selective cleavage of aryl-ether bonds US9718748B1 08/01/2017
System and method for detecting components of a mixture including a valving scheme for competition assays US9702871B1 07/11/2017
Catheterized plasma X-ray source US9681846B1 06/20/2017
Metal-organic frameworks for adsorption and separation of noble gases US9662632B1 05/30/2017
Fluid delivery manifolds and microfluidic systems US9579649B2 02/28/2017
Neural interface methods and apparatus to provide artificial sensory capabilities to a subject US9549704B1 01/24/2017
Miniature acoustic wave lysis system and uses thereof US9512421B1 12/06/2016
Colorometric detection of water using MOF-polymer films and composites US9347923B1 05/24/2016
Multiplexed microfluidic approach for nucleic acid enrichment US9322014B1 04/26/2016
Toxin activity assays, devices, methods and systems therefor US9304128B1 04/05/2016
Sub-wavelength antenna enhanced bilayer graphene tunable photodetector US9293627B1 03/22/2016
Multifunctional thin film surface US9157161B1 10/13/2015
Microfluidic device for acoustic cell lysis US9096823B1 08/04/2015
Methods and materials for deconstruction of biomass for biofuels production US9024111B1 05/05/2015
Microfluidic hubs, systems, and methods for interface fluidic modules US8940147B1 01/27/2015
Haptic device for telerobotic surgery US8924009B2 12/30/2014
Materials, methods and devices to detect and quantify water vapor concentrations in an atmosphere US8904850B1 12/09/2014
Methods, microfluidic devices, and systems for detection of an active enzymatic agent US8871496B1 10/28/2014
Dynamic tuning of chemiresistor sensitivity using mechanical strain US8846406B1 09/30/2014
Microelectroporation device for genomic screening US8828736B2 09/09/2014
Microfluidic device having an immobilized pH gradient and page gels for protein separation and analysis US8728290B1 05/20/2014
Dual-etalon cavity ring-down frequency-comb spectroscopy with broad band light source US8693004B2 04/08/2014
Hyperspectral stimulated emission depletion microscopy and methods of use thereof US8686363B1 04/01/2014
Optically transduced MEMS magnetometer US8674689B1 03/18/2014
High-frequency shear-horizontal surface acoustic wave sensor US8669688B1 03/11/2014
Coaxial microreactor for particle synthesis US8563325B1 10/22/2013
Stress-tuned conductor-polymer composite for use in sensors US8562878B1 10/22/2013
Apparatus and method for measuring single cell and sub-cellular photosynthetic efficiency US8481974B1 07/09/2013
Method of detecting cancer in a single cell using mitochondrial correlation microscopy US8472752B1 06/25/2013
Materials and methods for stabilizing nanoparticles in salt solutions US8461300B2 06/11/2013
High-frequency shear-horizontal surface acoustic wave sensor US8436509B1 05/07/2013
System for particle concentration and detection US8398839B1 03/19/2013
Microfluidic device having an immobilized pH gradient and PAGE gels for protein separation and analysis US8329016B1 12/11/2012
Portable dual field gradient force multichannel flow cytometer device with a dual wavelength low noise detection scheme US8293089B1 10/23/2012
Atomic magnetometer US8212556B1 07/03/2012
Method for detecting cancer in a single cell using mitochondrial correlation microscopy US8131112B1 03/06/2012
Method and apparatus for detecting an analyte US8065904B1 11/29/2011
Information-based self-organization of sensor nodes of a sensor network US8022987B2 09/20/2011
Electrode array for neural stimulation US8000804B1 08/16/2011
Simultaneous sample manipulation and sensing using surface acoustic waves US7878063B1 02/01/2011
System and method for statistically monitoring and analyzing sensed conditions US7877234B1 01/25/2011
System and method for statistically monitoring and analyzing sensed conditions US7865336B1 01/04/2011
System and method for statistically monitoring and analyzing sensed conditions US7756682B1 07/13/2010
Microfluidic device for the assembly and transport of microparticles US7744737B1 06/29/2010
Dielectrophoretic columnar focusing device US7713395B1 05/11/2010
Method of photocatalytic nanotagging US7704489B1 04/27/2010
Polymeric salt bridges for conducting electric current in microfluidic devices US7618524B1 11/17/2009
Surface engineered nanoparticles for improved surface enhanced Raman scattering applications and method for preparing same US7608461B1 10/27/2009
Complex admixtures of clathrate hydrates in a water desalination method US7560028B1 07/14/2009
Microfluidic microarray systems and methods thereof US7524672B2 04/28/2009
Method for detecting biomolecules US7410762B1 08/12/2008
Stationary phase deposition based on onium salts US7314505B1 01/01/2008
Method for siting detectors within a facility US7308374B2 12/11/2007
Electrokinetic pump US7297246B2 11/20/2007
Enzymatic cascade bioreactor US7264962B1 09/04/2007