|Abstract: ||The present invention relates to an acoustic lysis system including a
disposable cartridge that can be reversibly coupled to a platform having
a small, high-frequency piezoelectric transducer array. In particular,
the system releases viable DNA, RNA, and proteins from human or bacterial
cells, without chemicals or additional processing, to enable high-speed
sample preparation for clinical point-of-care medical diagnostics and use
with nano/microfluidic cartridges. Also described herein are methods of
making and using the system of the invention.