Patent • #US8191477B1. Microelectromechanical (MEM) apparatus and methods for operating, for preventing unintentional detonation of energetic components comprising pyrotechnic and explosive materials, such as air bag deployment systems, munitions and pyrotechnics. The MEM apparatus comprises an interrupting member that can be moved to block (interrupt) or complete (uninterrupt) an explosive train that...
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Microelectromechanical tunable inductor
Patent • #US7710232B1. A microelectromechanical tunable inductor is formed from a pair of substantially-identically-sized coils arranged side by side and coiled up about a central axis which is parallel to a supporting substrate. An in-plane stress gradient is responsible for coiling up the coils which. The inductance provided by the tunable inductor...
Microelectronics & MEMS
Technology Area • The Microelectronics & MEMS technology area contains solutions resulting from Sandia’s mission to develop trusted microsystems technologies for critical national security applications. It includes beyond leading-edge and increasingly powerful macro-system capabilities and functionalities. This technology area also contains specialized portfolios related to: Compound Semiconductor DevicesPhotonic Integrated Circuits & Silicon PhotonicsFabrication,...
Microelectroporation device for genomic screening
Patent • #US8828736B2. We have developed an microelectroporation device that combines microarrays of oligonucleotides, microfluidic channels, and electroporation for cell transfection and high-throughput screening applications (e.g. RNA interference screens). Microarrays allow the deposition of thousands of different oligonucleotides in microscopic spots. Microfluidic channels and microwells enable efficient loading of cells into the...
Microfabricated bulk wave acoustic bandgap device
Patent • #US7836566B1. A microfabricated bulk wave acoustic bandgap device comprises a periodic two-dimensional array of scatterers embedded within the matrix material membrane, wherein the scatterer material has a density and/or elastic constant that is different than the matrix material and wherein the periodicity of the array causes destructive interference of the...
Microfabricated bulk wave acoustic bandgap device
Patent • #US7733198B1. A microfabricated bulk wave acoustic bandgap device comprises a periodic two-dimensional array of scatterers embedded within the matrix material membrane, wherein the scatterer material has a density and/or elastic constant that is different than the matrix material and wherein the periodicity of the array causes destructive interference of the...
Microfabricated Field Calibration Assembly
Featured Opportunity • Reliable determination of the presence and/or quantity of a particular analyte in the field can be greatly enhanced if the analytical instrument is equipped with a time-of-use calibration standard. While proper calibration is necessary for reliability and accuracy, it can be challenging and cumbersome to provide such calibration in the...
Microfabricated field calibration assembly for analytical instruments
Patent • #US7913534B1. A microfabricated field calibration assembly for use in calibrating analytical instruments and sensor systems. The assembly comprises a circuit board comprising one or more resistively heatable microbridge elements, an interface device that enables addressable heating of the microbridge elements, and, in some embodiments, a means for positioning the circuit...
Microfabricated fuel heating value monitoring device
Patent • #US7708943B1. A microfabricated fuel heating value monitoring device comprises a microfabricated gas chromatography column in combination with a catalytic microcalorimeter. The microcalorimeter can comprise a reference thermal conductivity sensor to provide diagnostics and surety. Using microfabrication techniques, the device can be manufactured in production quantities at a low per-unit cost....
Microfabricated ion frequency standard
Patent • #US7859350B1. A microfabricated ion frequency standard (i.e. an ion clock) is disclosed with a permanently-sealed vacuum package containing a source of ytterbium (Yb) ions and an octupole ion trap. The source of Yb ions is a micro-hotplate which generates Yb atoms which are then ionized by a ultraviolet light-emitting diode...
Microfabricated ion trap chip with an integrated microwave antenna
Patent • #US10984976B1. An ion trap chip, which may be used for quantum information processing and the like, includes an integrated microwave antenna. The antenna is formed as a radiator connected by one of its ends to the center trace of a microwave transmission line and connected by its other end to...
Microfabricated ion trap chip with in situ radio-frequency sensing
Patent • #US11056332B1. A radio-frequency (RF) surface ion trap chip includes an RF electrode and an integrated capacitive voltage divider in which an intermediate voltage node is capacitively connected between the RF electrode and a ground. A sensor output trace is connected to the intermediate voltage node.
Microfabricated linear Paul-Straubel ion trap
Patent • #US7928375B1. An array of microfabricated linear Paul-Straubel ion traps can be used for mass spectrometric applications. Each ion trap comprises two parallel inner RF electrodes and two parallel outer DC control electrodes symmetric about a central trap axis and suspended over an opening in a substrate. Neighboring ion traps in...
Microfabricated particle focusing device
Patent • #US8425749B1. A microfabricated particle focusing device comprises an acoustic portion to preconcentrate particles over large spatial dimensions into particle streams and a dielectrophoretic portion for finer particle focusing into single-file columns. The device can be used for high throughput assays for which it is necessary to isolate and investigate small...
Microfabricated triggered vacuum switch
Patent • #US7714240B1. A microfabricated vacuum switch is disclosed which includes a substrate upon which an anode, cathode and trigger electrode are located. A cover is sealed over the substrate under vacuum to complete the vacuum switch. In some embodiments of the present invention, a metal cover can be used in place...
Microfluidic device for acoustic cell lysis
Patent • #US9096823B1. A microfluidic acoustic-based cell lysing device that can be integrated with on-chip nucleic acid extraction. Using a bulk acoustic wave (BAW) transducer array, acoustic waves can be coupled into microfluidic cartridges resulting in the lysis of cells contained therein by localized acoustic pressure. Cellular materials can then be extracted...
Microfluidic device for the assembly and transport of microparticles
Patent • #US7744737B1. A microfluidic device comprising independently addressable arrays of interdigitated electrodes can be used to assembly and transport large-scale microparticle structures. The device and method uses collective phenomena in a negatively polarized suspension exposed to a high-gradient strong ac electric field to assemble the particles into predetermined locations and then...
Microfluidic device having an immobilized pH gradient and page gels for protein separation and analysis
Patent • #US8728290B1. Disclosed is a novel microfluidic device enabling on-chip implementation of a two-dimensional separation methodology. Previously disclosed microscale immobilized pH gradients (IPG) are combined with perpendicular polyacrylamide gel electrophoresis (PAGE) microchannels to achieve orthogonal separations of biological samples. Device modifications enable inclusion of sodium dodecyl sulfate (SDS) in the second...
Microfluidic device having an immobilized pH gradient and PAGE gels for protein separation and analysis
Patent • #US8329016B1. Disclosed is a novel microfluidic device enabling on-chip implementation of a two-dimensional separation methodology. Previously disclosed microscale immobilized pH gradients (IPG) are combined with perpendicular polyacrylamide gel electrophoresis (PAGE) microchannels to achieve orthogonal separations of biological samples. Device modifications enable inclusion of sodium dodecyl sulfate (SDS) in the second...
Microfluidic hubs, systems, and methods for interface fluidic modules
Patent • #US8940147B1. Embodiments of microfluidic hubs and systems are described that may be used to connect fluidic modules. A space between surfaces may be set by fixtures described herein. In some examples a fixture may set substrate-to-substrate spacing based on a distance between registration surfaces on which the respective substrates rest....
Microfluidic microarray systems and methods thereof
Patent • #US7524672B2. Disclosed are systems that include a manifold in fluid communication with a microfluidic chip having a microarray, an illuminator, and a detector in optical communication with the microarray. Methods for using these systems for biological detection are also disclosed.
Microfluidic package and method of making the same
Patent • #US11554369B2. The present invention relates to encapsulated microfluidic packages and methods thereof. In particular embodiments, the package includes a device, a cradle configured to support the device, and a lid having a bonding surface configured to provide a fluidic seal between itself and the device and/or cradle. Other package configurations,...
Microfluidic package and method of making the same
Patent • #US10717079B2. The present invention relates to encapsulated microfluidic packages and methods thereof. In particular embodiments, the package includes a device, a cradle configured to support the device, and a lid having a bonding surface configured to provide a fluidic seal between itself and the device and/or cradle. Other package configurations,...
Microfluidic platform for multiplexed detection in single cells and methods thereof
Patent • #US10731205B2. The present invention relates to a microfluidic device and platform configured to conduct multiplexed analysis within the device. In particular, the device allows multiple targets to be detected on a single-cell level. Also provided are methods of performing multiplexed analyses to detect one or more target nucleic acids, proteins,...
Microfluidic platform for multiplexed detection in single cells and methods thereof
Patent • #US9957554B1. The present invention relates to a microfluidic device and platform configured to conduct multiplexed analysis within the device. In particular, the device allows multiple targets to be detected on a single-cell level. Also provided are methods of performing multiplexed analyses to detect one or more target nucleic acids, proteins,...
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