Devices, systems, and methods for conducting sandwich assays using sedimentation
| Patent Number: | 8,945,914 |
| Issued: | 2/3/2015 |
| Official Filing: | View the Complete Patent |
| Abstract: | Embodiments of the present invention are directed toward devices, systems, and method for conducting sandwich assays using sedimentation. In one example, a method includes generating complexes on a plurality of beads in a fluid sample, individual ones of the complexes comprising a capture agent, a target analyte, and a labeling agent. The plurality of beads including the complexes may be transported through a density media, wherein the density media has a density lower than a density of the beads and higher than a density of the fluid sample, and wherein the transporting occurs, at least in part, by sedimentation. Signal may be detected from the labeling agents of the complexes. |
| Filed: | 9/28/2010 |
| Application Number: | 12/891,977 |
| Related Opportunity: |
ViralFx SpinDx™: Point-of-Care Diagnostics Using Centrifugal Microfluidics |
| Government Interests: | STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |