| Abstract: Embodiments of the present invention are directed toward devices, system
and method for conducting toxin activity assay using sedimentation. The
toxin activity assay may include generating complexes which bind to a
plurality of beads in a fluid sample. The complexes may include a target
toxin and a labeling agent, or may be generated due to presence of active
target toxin and/or labeling agent designed to be incorporated into
complexes responsive to the presence of target active toxin. The
plurality of beads including the complexes may be transported through a
density media, wherein the density media has a lower density than a
density of the beads and higher than a density of the fluid sample, and
wherein the transporting occurs, at least in part, by sedimentation.
Signal may be detected from the labeling agents of the complexes. |
| Filed: 1/16/2014 |
| Application Number: 14/157278 |
| This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |
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