Shape-preserving transformations of organic matter and compositions thereof

DWPI Title: Transforming organic matter into organic-inorganic composites, inorganic or carbon replicas, by treating biological sample comprising cells with chemical or biological agents, and introducing silicic acid compound to biological sample
Abstract: The present invention relates to methods of transforming organic matter into organic-inorganic composites, inorganic replicas, or conductive replicas. Organic matter, such as biological cells and tissue and organs, can be converted into such composites and replicas using the methods described herein. In particular, such methods transform organic matter (into inorganic, organic-inorganic, or conductive constructs), while simultaneously preserving microscopic and/or macroscopic structural detail.
Use: The method is useful for transforming organic matter into organic-inorganic composites, inorganic or carbon replicas.
Novelty: Method involves treating a biological sample comprising one or more cells, with one or more chemical or biological agents to alter shape of the biological sample, and introducing a silicic acid compound to the biological sample, thus forming one or more conformal silica nanolayers on and within the one or more cells by condensing a silicic acid chosen from orthosilicic acid, metasilicic acid, disilicic acid, and pyrosilicic acid, thus forming a silica composite.
Filed: 7/9/2015
Application Number: US14795366A
Tech ID: SD 13102.0
This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention.
Data from Derwent World Patents Index, provided by Clarivate
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