| Abstract: The present application relates to microfabricated columns having a
sealed flow channel. In particular, the channel is sealed during dicing,
thereby preventing debris from accumulating within channels. In use, the
seal is ruptured mechanically to connect one or more fluidic connections,
which deliver analytes to the flow channel. Additional details are
provided for making and using sealed columns. |
| Filed: 1/11/2016 |
| Application Number: 14/992871 |
| This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |
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