Real time autonomous surveillance of pathogens
| DWPI Title: System for detecting presence of pathogens including virus, parasite or bacteria in arthropod vectors, preferably mosquitoes, comprises port that receives mosquito or tick, circular carousel tray including cartridges, stepper motor that rotates circular carousel tray and processing module |
| Abstract: The present invention relates, in part, to systems configured to obtain samples from an organism in an autonomous manner. Such systems can employ a cartridge configured to provide bait to attract an organism, as well as channels to store and/or test samples obtained from the organism. |
| Use: System for detecting the presence of pathogens including viruses, parasites or bacteria in arthropod vectors, preferably mosquitoes. |
| Advantage: The system is configured to obtain samples from an organism in an autonomous manner, thus minimizing human contact and exposure to pathogens and simplifying sample collection and testing, and employs a cartridge configured to provide bait to attract an organism and channels to store and/or test samples obtained from the organism. |
| Novelty: System comprises (a) a port that receives a mosquito or tick, (b) a circular carousel tray including cartridges that are arranged symmetrically around a center of the circular tray and comprise a cartridge, (c) a stepper motor that rotates the circular carousel tray, where the cartridges progress through different stations of the system as the circular carousel tray is rotated by the stepper motor and the stations include (i) a bait loading station that loads bait into a feeding well of the cartridge, (ii) an access station, (iii) a sample preparation station that causes an agent retained in an assay channel of the cartridge, (iv) a mixing station that includes a mixer to mix the sample such that an assay for detecting a target nucleic acid is conductible, (v) a heating station including a heater to provide assay conditions, and (vi) a detection station including a light source, and (d) a processing module. |
| Filed: 4/12/2018 |
| Application Number: US15951920A |
| Tech ID: SD 13973.1 |
| This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |
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