Preconcentration and separation of analytes in microchannels

Patent Number: 7,828,948
Issued: 11/9/2010
Official Filing: View the Complete Patent
Abstract: Disclosed herein are methods and devices for preconcentrating and separating analytes such as proteins and polynucleotides in microchannels. As disclosed, at least one size-exclusion polymeric element is adjacent to processing area or an assay area in a microchannel which may be porous polymeric element. The size-exclusion polymeric element may be used to manipulate, e.g. concentrate, analytes in a sample prior to assaying in the assay area.
Filed: 9/29/2006
Application Number: 11/536,753
Related Opportunity: Microscale Immune and Cell Analysis (MICA)
Rapid Automated Point-of-Care System (RapiDx)
Government Interests: STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention.