Preconcentration and separation of analytes in microchannels
| Patent Number: | 7,828,948 |
| Issued: | 11/9/2010 |
| Official Filing: | View the Complete Patent |
| Abstract: | Disclosed herein are methods and devices for preconcentrating and separating analytes such as proteins and polynucleotides in microchannels. As disclosed, at least one size-exclusion polymeric element is adjacent to processing area or an assay area in a microchannel which may be porous polymeric element. The size-exclusion polymeric element may be used to manipulate, e.g. concentrate, analytes in a sample prior to assaying in the assay area. |
| Filed: | 9/29/2006 |
| Application Number: | 11/536,753 |
| Related Opportunity: |
Microscale Immune and Cell Analysis (MICA) Rapid Automated Point-of-Care System (RapiDx) |
| Government Interests: | STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |