Methods of transfection using sonoporation
| Patent Number: | 11834650 |
| Issued: | 12/5/2023 |
| Official Filing: | View the Complete Patent |
| Abstract: | The present invention relates to methods of transforming a cell by use of an acoustic transducer. In particular embodiments, the radiofrequency signal to the transducer can be tuned to provide optimal membrane disruption of the cell; and an agent, such as a nucleic acid, can then be delivered to the cell. |
| Filed: | 6/20/2019 |
| Government Interests: | STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |