Terpene synthases for biofuel production and methods thereof
| DWPI Title: New isolated, genetically engineered organism comprising exogenous terpenoid precursor or exogenous enzyme configured to synthesize terpenoid precursor, and exogenous endophytic fungal terpene synthase, used to produce terpenoid compounds |
| Abstract: The present invention relates to terpene synthases capable of degrading precursors into biofuel compounds, such as terpenoid compounds. In one instance, a transformed organism can include such terpene synthases, as well as vectors encoding such synthases. Methods of employing such synthases and organisms are also described herein. |
| Use: The organism is useful for producing at least one of terpenoid compounds comprising a monoterpene, a sesquiterpene and a diterpene (claimed), where the terpenoid compounds are useful for production of high energy density fuels e.g. aviation fuels and chemical intermediates. |
| Advantage: The organism: diminishes the processing cost and improves the overall process feasibility; and is robust. |
| Novelty: Isolated, genetically engineered organism comprising: an exogenous terpenoid precursor, an exogenous enzyme configured to synthesize a terpenoid precursor, or a nucleic acid encoding the exogenous enzyme; and an exogenous endophytic fungal terpene synthase or a nucleic acid encoding the exogenous endophytic fungal terpene synthase, is new. The exogenous endophytic fungal terpene synthase is pinene synthase, guaiene synthase, pinene and guaiene synthase, caryophyllene synthase, chamigrene synthase, chamigrene and pinene synthase, gurjunene synthase, gurjunene and pinene synthase, gumunene (sic) synthase, selinene synthase or isoledene synthase, or its bifunctional synthase. |
| Filed: 3/10/2016 |
| Application Number: US15066651A |
| Tech ID: SD 13315.1 |
| This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |
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