Biochemical upgrading of high-protein biomass and grain products

DWPI Title: New isolated, genetically engineered organism comprising e.g. modified alcohol dehydrogenase having increased reactivity with NADH to provide chemical intermediates, fuels, amino acids, nutrients or to produce ethanol
Abstract: The present invention relates to methods of upgrading biomass to provide useful chemical intermediates, fuels, amino acids, nutrients, etc. In particular examples, the biomass is a by-product of ethanol production and is mainly used as high-protein feed. Described herein are methods for upgrading such biomass, such as by implementing pre-treatment conditions and by employing fermentation conditions including modified organisms.
Use: The microorganism is useful for providing chemical intermediates, fuels, amino acids, nutrients, and for producing ethanol.
Advantage: The microorganism has a modified alcohol dehydrogenase having increased reactivity with NADH, as compared to a wild-type alcohol dehydrogenase and a modified ketol-acid reductor-isomerase having increased reactivity with NADH, as compared to a wild-type ketol-acid reductor-isomerase.
Novelty: Isolated, genetically engineered organism comprising a modified alcohol dehydrogenase having increased reactivity with NADH, as compared to a wild-type alcohol dehydrogenase and a modified ketol-acid reductor-isomerase having increased reactivity with NADH, as compared to a wild-type ketol-acid reductor-isomerase, is new.
Filed: 5/7/2020
Application Number: US16868670A
Tech ID: SD 13872.2
This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention.
Data from Derwent World Patents Index, provided by Clarivate
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