Crop protection in algae by exogenous terpene expression
| DWPI Title: New isolated, genetically engineered organism comprising first exogenous fungal terpene synthase or nucleic acid encoding first exogenous fungal terpene synthase, for producing terpenoid or sesquiterpene use as biocide, protecting algal culture |
| Abstract: The present disclosure relates to terpene synthases capable of producing terpenoids. In one instance, a transformed organism can include terpene synthases or vectors encoding such synthases. One method of employing such synthases and organisms includes protecting an algal culture, in which the produced terpenoid can act as a biocide. |
| Use: Isolated, genetically engineered organism for producing terpenoid or sesquiterpene (claimed), use as biocide, protecting algal culture. |
| Advantage: The isolated, genetically engineered organism provides a stabilized culture for algal culture, effectively degrades an endogenous terpenoid precursor or an exogenous terpenoid precursor, e.g., as compared to an organism lacking the exogenous enzyme configured to synthesize a terpenoid precursor and lacking the nucleic acid encoding the exogenous enzyme. |
| Novelty: Isolated, genetically engineered organism comprising a first exogenous fungal terpene synthase or a nucleic acid encoding the first exogenous fungal terpene synthase, is new. The first exogenous fungal terpene synthase comprises a polypeptide sequence having at least 90% sequence identity comprising 313 amino acids of (SEQ ID NO: 1), given in the specification, or the nucleic acid encoding the first exogenous fungal terpene synthase comprising a nucleic acid sequence encoding a polypeptide sequence having at least 90% sequence identity to (SEQ ID NO: 1), and a second exogenous fungal terpene synthase or a nucleic acid encoding the second exogenous fungal terpene synthase. The second exogenous fungal terpene synthase comprises a polypeptide sequence having at least 90% sequence identity comprising 334 amino acids of (SEQ ID NO: 2), given in the specification, or the nucleic acid encoding the second exogenous fungal terpene synthase comprises a nucleic acid sequence. |
| Filed: 1/20/2021 |
| Application Number: US17153106A |
| Tech ID: SD 14795.0 |
| This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |
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