Linear peptides that mimic structural epitopes for antibody assays
| Patent Number: | 10,267,788 |
| Issued: | 4/23/2019 |
| Official Filing: | View the Complete Patent |
| Abstract: | A method including identifying one or more structures in adjacent sequences of one or more proteins that can be mimicked by a peptide; and assembling a peptide that mimics the one or more secondary structures. A method including assembling epitopes of linked pairs of discontiguous peptide subsequences that mimic one or more structures in sequences of a protein; and assaying antibodies against the epitopes. |
| Filed: | 1/20/2014 |
| Application Number: | 14/159,308 |
| Government Interests: | STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |