System for particle concentration and detection
| DWPI Title: System for concentrating and detecting e.g. virus in surrounding atmosphere, has data acquisition recorder to control operation of valves and light source and to alert if running average baseline value signal is beyond preset threshold |
| Abstract: A new microfluidic system comprising an automated prototype insulator-based dielectrophoresis (iDEP) triggering microfluidic device for pathogen monitoring that can eventually be run outside the laboratory in a real world environment has been used to demonstrate the feasibility of automated trapping and detection of particles. The system broadly comprised an aerosol collector for collecting air-borne particles, an iDEP chip within which to temporarily trap the collected particles and a laser and fluorescence detector with which to induce a fluorescence signal and detect a change in that signal as particles are trapped within the iDEP chip. |
| Use: System for concentrating and detecting particles such as spores, cells, bacteria, pathogens and virus contained in surrounding atmosphere, used in governmental and commercial infrastructure protection initiatives. |
| Advantage: The programmable data acquisition recorder controls the operation of valves and light source and signals an alert if running average baseline value signal from detector is beyond preset threshold, so that the fast and accurate presumptive identification of particles can be detected. |
| Novelty: The system has an insulator-based dielectrophoretic (iDEP) microfluidic chip comprising an inlet and an outlet port in which tube electrodes are arranged. An aerosol collector connects with fluid pumps and iDEP chip by conduits and valves. A particle detector generates electrical analog output signal proportional to intensity of emitted light of fluid sample. A programmable data acquisition recorder controls the operation of valves and light source and signals an alert if running average baseline value signal from detector is beyond preset threshold. |
| Filed: 6/3/2010 |
| Application Number: US2010793370A |
| Tech ID: SD 11293.1 |
| This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |
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