Abstract: | A system and methods for detection of a nucleic acid including forming a
plurality of nucleic acid detection complexes are described, each of the
complexes including a nucleic acid analyte, a detection agent and a
functionalized probe. The method further including binding the nucleic
acid detection complexes to a plurality of functionalized particles in a
fluid sample and separating the functionalized particles having the
nucleic acid detection complexes bound thereto from the fluid sample
using a density media. The nucleic acid analyte is detected by detecting
the detection agent. |