| Abstract: The present invention, in part, relates to an apparatus having a
single-use, normally-closed fluidic valve that is initially maintained in
the closed position by a valve element bonded to an adhesive coating. The
valve is opened using a magnetic force. The valve element includes a
magnetic material or metal. In some examples, the valve is opened by
bringing a magnet in proximity to the valve element to provide a magnetic
force that delaminates the valve element from the adhesive coating. In
particular, the apparatus can be useful for on-chip amplification and/or
detection of various targets, including biological targets and any
amplifiable targets. Such apparatuses and methods are useful for in-field
or real-time detection of targets, especially in limited resource
settings. |
| Filed: 1/16/2014 |
| Application Number: 14/157335 |
| This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |
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