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Microfluidic platform for multiplexed detection in single cells and methods thereof

United States Patent

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10,731,205
August 4, 2020
View the Complete Patent at the US Patent & Trademark Office
The present invention relates to a microfluidic device and platform configured to conduct multiplexed analysis within the device. In particular, the device allows multiple targets to be detected on a single-cell level. Also provided are methods of performing multiplexed analyses to detect one or more target nucleic acids, proteins, and post-translational modifications.
15/925,389
March 19, 2018
1/1;
C12Q 1/6837 (20180101); C12Q 1/6816 (20180101); G01N 15/14 (20060101); C40B 30/04 (20060101); G01N 15/10 (20060101); B01L 3/00 (20060101); G01N 33/536 (20060101); C12Q 1/6841 (20180101); C12Q 1/6804 (20180101); C12Q 1/6844 (20180101);
STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention.