| Abstract: A variety of polymers and copolymers suitable for use as biologically
compatible constructs and, as a non-limiting specific example, in the
formation of degradable tissue scaffolds as well methods for synthesizing
these polymers and copolymers are described. The polymers and copolymers
have degradation rates that are substantially faster than those of
previously described polymers suitable for the same uses. Copolymers
having a synthesis route which enables one to fine tune the degradation
rate by selecting the specific stoichiometry of the monomers in the
resulting copolymer are also described. The disclosure also provides a
novel synthesis route for maleoyl chloride which yields monomers suitable
for use in the copolymer synthesis methods described herein. |
| Filed: 1/6/2014 |
| Application Number: 14/147983 |
| This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |
| Attribution for Derwent World Patents Index Records published on Sandia ® Clarivate. All rights reserved. Republication or redistribution of Clarivate content, including by framing or similar means, is prohibited without the prior written consent of Clarivate. Clarivate and its logo, as well as all other trademarks used herein are trademarks of their respective owners and used under license. |