Abstract: | Embodiments of microfluidic hubs and systems are described that may be
used to connect fluidic modules. A space between surfaces may be set by
fixtures described herein. In some examples a fixture may set
substrate-to-substrate spacing based on a distance between registration
surfaces on which the respective substrates rest. Fluidic interfaces are
described, including examples where fluid conduits (e.g. capillaries)
extend into the fixture to the space between surfaces. Droplets of fluid
may be introduced to and/or removed from microfluidic hubs described
herein, and fluid actuators may be used to move droplets within the space
between surfaces. Continuous flow modules may be integrated with the hubs
in some examples. |