Shape-preserving polymeric replication of biological matter
| Patent Number: | 10,947,349 |
| Issued: | 3/16/2021 |
| Official Filing: | View the Complete Patent |
| Abstract: | The present invention relates to a method of forming silica nanolayers on or within a biological sample, thereby capturing structural details that are present in the sample. The resultant silica composite or silica replica, in turn, can be employed as a template for a replica having those structural details captured in a polymer. Also provided herein are synthetic constructs including a polymeric replica, which can have any useful feature (e.g., oxygen-binding capacity). |
| Filed: | 12/11/2019 |
| Application Number: | 16/711,150 |
| Government Interests: | STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |