Real-time patch-clamp sensing of transport across a barrier tissue
| Patent Number: | 11885793 |
| Issued: | 1/30/2024 |
| Official Filing: | View the Complete Patent |
| Abstract: | The present disclosure relates to methods, apparatuses, and systems to measure one or more electrical signals from a cultured cell layer. In some embodiments, such electrical signals can be indicative of transport or lack of transport of an agent through the cell layer. |
| Filed: | 10/19/2020 |
| Government Interests: | STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under Contract No. DE-NA0003525 awarded by the United States Department of Energy/National Nuclear Security Administration. The Government has certain rights in the invention. |