|Abstract: ||The present invention, in part, relates to methods and apparatuses for
on-chip amplification and/or detection of various targets, including
biological targets and any amplifiable targets. In some examples, the
microculture apparatus includes a single-use, normally-closed fluidic
valve that is initially maintained in the closed position by a valve
element bonded to an adhesive coating. The valve is opened using a
magnetic force. The valve element includes a magnetic material or metal.
Such apparatuses and methods are useful for in-field or real-time
detection of targets, especially in limited resource settings.