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Methods for treating diseases related to the wnt pathway

United States Patent

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April 21, 2020
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The present invention relates to methods for treating a disease, in which the disease arises from dysregulation of the Wnt signaling pathway. In some instances, the disease can be treated by administering a Wnt pathway inhibitory compound. In other instances, the method optionally includes conducting a genome-wide screening to determine one or more genes resulting in a reduced disease state and then identifying the gene(s) as being involved in the Wnt signaling pathway.
July 7, 2016
A61K 31/40 (20060101); A61K 31/4439 (20060101); A61K 31/136 (20060101); C12Q 1/6883 (20180101); A61K 31/475 (20060101); A61K 31/407 (20060101); A61K 38/17 (20060101); A61K 31/425 (20060101); A61K 31/42 (20060101); A61K 31/18 (20060101); A61K 31/135 (20060101); A61K 31/519 (20060101); A61K 31/47 (20060101); A61K 31/44 (20060101); A61K 31/35 (20060101); A61K 31/235 (20060101);
STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under contract no. DE-AC04-94AL85000 awarded by the U.S. Department of Energy to Sandia Corporation. The Government has certain rights in the invention.