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DNA/RNA sequencing using a semiconducting nanopore

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United States Patent

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9,988,677
June 5, 2018
View the Complete Patent at the US Patent & Trademark Office
The present disclosure provides novel apparatus including, though not necessarily limited to, biosensors utilizing semiconductor materials in electrolyte solutions and methods for using the same. The biosensors rely on a unique property wherein a charged body in the electrolyte solution produces a detectable change in the local conductivity of the semiconductor as the body approaches or travels near the semiconductor.
14/ 735,898
June 10, 2015
1/1
G01N 27/00 (20060101)G01N 25/18 (20060101)C12Q 1/68 (20180101)G01Q 60/24 (20100101)G01N 27/327 (20060101)G01N 33/487 (20060101)
;422/82.02,68.1;436/43,149,94;205/775;435/6.11;977/700,704,904,953,958
STATEMENT REGARDING GOVERNMENT SPONSORED RESEARCH This invention was made with Government support under Grant No. DE-AC04-94AL85000 awarded by the Department of Energy and Sandia National Labs and CBET0844645 awarded by the National Science Foundation. The U.S. Government has certain rights in this invention.